The results showed that para-carcinoma tissues with tRF-29 upregulation exhibited low expression of KIF14, MMP-2, and p-AKT(S473), and high expression of P27; while in cancer tissues with tRF-29 downregulation showed significantly high expression of KIF14, MMP-2, and p-AKT(S473), and low level of P27 (Supplementary Fig. 5). Here, MMP2 is linked to cancer.