For example, only scPrediXcan identifies two genes on chromosome 16 that have been implicated in SLE pathogenesis: PYCARD (also named ASC) in CD4+ α-β T cells (p = 7.8 × 10−48) and ITGAM in CD14+ monocytes (p = 4.3 × 10−41).35 Here, ITGAM is linked to systemic lupus erythematosus.