KLK3 and benign prostatic hyperplasia: Clinical predictors like the international prostate symptom score (IPSS) [14], quality of life (QoL) scores, and pertinent biomarkers including prostate-specific antigen (PSA) levels [15], white blood cell count (WBC) [16], creatinine (Cr) [17], and hemoglobin (Hb) [18] are critical, especially in BPH with bladder diverticula.