To investigate the expression of FUT8 mRNA, we analyzed date in the Timer 2.0 online database, which showed that FUT8 was widespread expressed in human pan-cancer tissues, with significantly higher expression in BRCA, CHOL, COAD, HNSC, KIRP, LUAD, LUSC and STAD (all p < 0.001), PCPG and READ (p < 0.01) were expressed higher than normal tissues, significantly lower in KICH (p < 0.001), PRAD and UCEC (p < 0.01), and higher in metastasis-associated SKCM (p < 0.001) than without metastasis, and the differences in expression were all statistically significant (Fig 2a). This evidence concerns the gene FUT8 and cancer.