DGKD and Hypercalciuria: Furthermore, DGKδ W1181 was associated with hypercalciuria in this study, and rs838717 has been reported to be associated with higher urinary calcium excretion in a small cohort (17), although associations of 24-hour urinary calcium excretion and rs838717 were not replicated in a GWAS of approximately 6,500 individuals (37).