SLC2A1 and head and neck squamous cell carcinoma: Furthermore, HNSCC exhibited significantly elevated SLC2A1 mRNA expression compared with both normal esophageal mucosa (Fig. 1D) and pan-cancer cell lines (Supplementary Fig. S1D), and GLUT1 protein expression was observed to be higher in HNSCC tumors than in normal tissue (Supplementary Fig. S1E).