Wheat germ agglutinin (WGA) staining showed that cardiomyocyte hypertrophy was evident in Aars2 cKO hearts (Figure 1K), and Masson staining indicated severe cardiac fibrosis in Aars2 cKO hearts compared with Aars2fl/fl hearts (Figure 1L) at 28 d after induction. This evidence concerns the gene AARS2 and fibrosis.