In addition to PNPLA3 p.I148M, other variants such as MBOAT7 (membrane‐bound O‐acyltransferase domain‐containing protein 7) p.G17E, TM6SF2 (Transmembrane 6 superfamily 2) p.E167K and APOE rs429358 (apolipoprotein E) have also been shown to increase the risk of liver injury in patients with MASLD and alcohol‐associated liver diseases.384, 385, 386. This evidence concerns the gene APOE and metabolic dysfunction-associated steatotic liver disease.