TNF and Hypertension: Also, it is associated with a reduction in LDL cholesterol and postprandial lipemia in PlwO, improvement in the components of the metabolic syndrome (increase in HDL cholesterol, decrease in triglycerides, decrease in arterial hypertension) and an improvement in insulin sensitivity, inflammation (C reactive protein, IL‐6, IL‐18, TNF‐α) and endothelial function.610