Emerging evidence is reporting how cTnI and cTnT are not clinically interchangeable, both diagnostically or prognostically.10,26–32 In light chain amyloidosis, studies showed a better prognostic performance of cTnT compared with cTnI,33 and this was confirmed in a more recent study with hs-cTn assays.34 These aspects have not been addressed in ATTRwt-CM. The gene discussed is TNNT2; the disease is AL amyloidosis.