Given the prominence of IL-6 in breast cancer migration, invasion and metastasis (Zhou et al., 2017; Hou et al., 2018; Johnson et al., 2018; Cho et al., 2020; Chen et al., 2022; Manore et al., 2022; Radharani et al., 2022), we evaluated the Normalised Enrichment Score (NES) of the IL-6 signalling in our data set. This evidence concerns the gene IL6 and breast cancer.