SLC39A4 and acrodermatitis enteropathica: It contrasts with the classic presentation of acrodermatitis enteropathica (AE), which is a rare autosomal recessive condition secondary to SLC39A4 gene mutation carried by the infant encoding zinc/iron-regulated transporter-like protein (hZIP4), a ZnT within the intestinal epithelium.4 This inherited condition tends to occur in newborns who are either fed through formula or once they are weaned off from breastfeeding.