The expression of MRPL35 is significantly upregulated in gastric cancer tissues and is closely associated with patient age, lymph node metastasis, and pathological tumor-node-metastasis (TNM) staging, both in vivo and in vitro experiments have shown that knocking down MRPL35 significantly inhibits the proliferation and colony formation of gastric cancer cells and induces apoptosis (72). The gene discussed is MRPL35; the disease is gastric cancer.