IL6 and non-small cell lung carcinoma: Furthermore, in murine studies, Lee et al. established that ginseng berry polysaccharide partially elicited a pro-immune response by augmenting the expression of IL-6, IL-12, and TNF-α in mouse peritoneal TAM, and prompted the polarization of TAM towards the M1 phenotype, thereby emerging as a potential therapeutic agent for immunotherapy in NSCLC (134).