In our paper, it was found that the sepsis group possessed higher APACHE II scores, SOFA scores, and serum Lac, CRP, and PCT levels, and lower 25(OH)D levels versus the control group; the death group had higher APACHE II scores, SOFA scores, and serum Lac, CRP, and PCT levels, and lower 25(OH)D levels versus the survival group. This evidence concerns the gene CRP and Sepsis.