The ROC curve analysis results showed that the AUC for diagnosing sepsis with the AA genotype at the VDBP gene rs4588 locus was 0.579 (95% CI: 0.501∼0.656), with a sensitivity of 52.70% and a specificity of 63.00% (P < 0.05) (Table 4; Figure 1). Here, GC is linked to Sepsis.