Numerous target antigens for AECAs in vasculitis have been studied, including HLA in Takayasu’s arteritis and KD (30, 31), β2-GPI in GCA (32) and IgAV (33), DNA, PR3, MPO and phospholipid in anti-neutrophil cytoplasmic antibodies-associated vasculitis (34), HSP60, HSP70 in GCA and KD (35). The gene discussed is MPO; the disease is temporal arteritis.