Acute Phase Proteins such as a-2-macroglobulin (A2M), C-Reactive Protein, Serum Amyloid P (SAP), haptoglobin, ferritin, sTFR, apotransferrin, hepcidin, S100A8, and S100A9 are analyzed to potentially establish these markers for early TB prognosis in HIV-positive patients. The gene discussed is S100A8; the disease is tuberculosis.