Lovastatin modulates cholesterol biosynthesis and induces apoptosis in neuroblastoma; hyperactive Akt1 signaling promotes tumor progression in RMS; mesenchymal neuroblastomas depend on HMGCR-driven protein geranylgeranylation; inhibition of the mevalonate pathway reduces OS metastasis by suppressing Yes-associated protein 1 (YAP1) activity. Here, AKT1 is linked to neoplasm.