↑Functionally active CACs and FMD compared with placebo; attenuation of the effect of cream (fat) consumption on FMD impairment; no significant effect on biomarkers of low‐grade inflammation (CRP, SAA, IL‐1β, IL‐6, IL‐8, TNF‐α) and endothelial dysfunction (sICAM, sVCAM, E‐sel, ET‐1); no effect on TCh, LDL, HDL, TG, glucose or insulin level in plasma. The gene discussed is SELE; the disease is endothelial dysfunction.