To comprehensively validate the reliability of our screening results and their tissue-specific expression patterns, we performed expression validation and diagnostic performance evaluation of the four oxidative stress-related hub genes (CD44, ITGB2, MICB, and RAC2) identified from the glomerular dataset using ANCA-associated vasculitis tubulointerstitial datasets (GSE104954 and GSE108112). The gene discussed is ITGB2; the disease is anti-neutrophil cytoplasmic antibody-associated vasculitis.