Downregulating circ-MBOAT2 inhibited TLK1 expression, and this inhibition was mitigated by miR-664b-3p inhibitor (Fig. 5F), and circ-MBOAT2 and TLK1 levels in NSCLC tissues were positively correlated (Fig. 5G). Here, TLK1 is linked to non-small cell lung carcinoma.