Recent studies have shown that TAMs play an important role in immune-mediated cancer control through the secretion of multiple cytokines, including IL-6, IL-10, transforming growth factor β (TGF-β), tumor necrosis factor α (TNF-α), C-C chemokine motif ligand 18 (CCL18) and CCL22 [15, 17, 18]. The gene discussed is TNF; the disease is cancer.