WDR62 and colorectal cancer: In addition, knockdown of WDR62 reversed the resistance in gastric cancer cells to 5-FU, cis-diaminodichloroplatinum (CDDP), and adriamycin (ADM) [26], and elevated expression of WDR62 led to resistance to oxaliplatin and cetuximab in colorectal cancer patients [27–28].