ALB and acute kidney injury: Elevated urinary biomarkers IGFBP-7 and TIMP-2 further reflect renal tubular damage, consistent with their role as markers of acute kidney injury [2].Urinary biomarkers IGFBP-7 and TIMP-2 showed strong correlations with renal dysfunction (negative correlations with eGFR and albumin, positive correlations with creatinine) and disease progression (positive correlations with plasma cell percentage and LDH).