PVR and neoplasm: Interestingly, the weaker correlations of PVR serum levels with these parameters (TLC: r = −0.002, p = 0.988; hemoglobin: r = −0.024, p = 0.869; platelet count: r = −0.091, p = 0.530) suggest that PVR gene expression may be a more sensitive indicator of hematological involvement, possibly reflecting its direct role in tumor-microenvironment interactions [31].