Notably, Lcn2–/– mice exhibited remarkable reductions in skin lesion thickness (Fig. S3), desquamation, and erythema, along with a decrease in the mouse psoriasis severity score (P = 0.0209, Fig. 7C, D) [36], without any impact on body weight (the detailed scoring criteria are provided in Table S5). This evidence concerns the gene LCN2 and Erythema.