Pearson’s correlation coefficient and scatter plot indicated that plasma FBLN5 concentration was positively correlated with the H score for FBLN5 in primary gastric tissue (R = 0.671, P = 0.034) (Fig. 4f), suggesting the potential utilization of plasma FBLN5 as a biomarker for cancer detection and tumor progression in gastric cancer. This evidence concerns the gene FBLN5 and neoplasm.