SLC6A6 and leukemia: To determine whether small-molecule inhibitors of TAUT can effectively block leukaemia growth, we used two well-characterized structural analogues of taurine that inhibit uptake: 6-aminomethyl-3-methyl-4H-1,2,4-benzothiadiazine-1,1-dioxide hydrochloride35 (TAG) and guanidinoethyl sulphonate36 (GES; Extended Data Fig. 8d,e).