T-cell receptor β chain (Tcrb)–/– STING N153S mice that lack αβ T cells only have mild lung disease or no disease at all, and recombination-activating gene 1 (Rag1)–/– STING N153S mice exhibit no histologic sign of lung inflammation, suggesting that T cells play a dominant role in promoting lung disease (Luksch et al., 2019). The gene discussed is RAG1; the disease is lung disorder.