FBXW7 and testicular germ cell tumor: The correlation and role of aberrant miRNAs with different types of TGCT has been broadly reported in the past few years11; for instance, miR-371a-3p, miRNA-367–3p, miR-371A-3p, miR-372–3p, and miR-373–3p are provided with superior sensitivity and specificity for TGCT diagnosis and can be used as novel biomarkers.12, 13, 14 microRNA-223–3p modulates TGCT cell advancement via targeting FBXW7 to exert a carcinogenic role,15 while miR-509–5p represses TGCT cell progression via targeting MDM2 to play an anticancer role.16