EGFR and neoplasm: Hence, it is reasonableto assume that the large concentrations of hEGF and Z03115 administereddecreased the concentration of EGFR available for binding (i.e., RA).This time-dependent change in BP demonstrates the potential of PAIto dynamically track changes in tumor RA in vivo.Although the trend of BP–time curves was consistent betweenBPdeconv and BPratio, the BPdeconv-time curves appeared to be more stable, suggesting the superiorityof BPdeconv for in vivo RA assessment.