KEGG pathway analysis revealed that the upregulated proteins were significantly enriched in ‘rheumatoid arthritis’ (hsa05323; 7 proteins), followed by ‘viral protein interaction with cytokine and cytokine receptor’ (hsa04061), ‘IL-17 signaling pathway’ (hsa04657), ’malaria’ (hsa05144), ‘cytokine-cytokine receptor interaction’ (hsa04060), and ‘chemokine signaling pathway’ (hsa04062), (Fig 7H). The gene discussed is IL17A; the disease is malaria.