Additionally, the bioinformatics analysis of TISIDB database (http://cis.hku.hk/TISIDB/) showed that POLA2 expression was significantly correlated with the abundance of tumor-infiltrating CD8+ T cells and CD4+ T cells, but had no correlation with macrophage abundance in PCa (Fig. 7A). This evidence concerns the gene POLA2 and posterior cortical atrophy.