Moreover, subcutaneous tumors from MHCC‐97H cells co‐injected with MTFR2‐deficient HSCs exhibited lower levels of α‐SMA and COL1 compared to tumors co‐injected with WT HSCs, suggesting that MTFR2 deficiency in HSCs diminishes their capacity to promote tumor growth in vivo. Here, ACTA1 is linked to neoplasm.