CGAS and bacterial infectious disease: The cGAS (cyclic GMP‐AMP synthase) protein detects cytosolic DNA, activating the STING (stimulator of interferon genes) pathway to induce immune responses and apoptosis via downstream effectors like IRF3 and NF‐κB.[30, 31] Although its role in immunity is well‐documented, the involvement of cGAS‐STING in apoptosis during bacterial infections is a recent discovery and remains understudied.[32, 33] In particular, how bacteria exploit this pathway to induce apoptosis represents a significant gap in host‐pathogen interaction research.