Therefore, VCAM-1 and ICAM-1 can be considered as predictors of CVD events and closely related to the atherosclerosis development.32N. sativa is a well-tolerated and safe herb and most of its helpful medicinal properties are due to volatile oil, of that TQ is a main component.33 Different mechanisms are indicated for potential ameliorative effect of N. sativa or its bioactive agent TQ on adhesion molecules. Here, VCAM1 is linked to atherosclerosis.