CD4 and neoplasm: In contrast, in LGG, LSM2 expression positively correlated with tumour purity (r = 0.154, p < 0.001) and CD4+ T cell infiltration (r = 0.161, p < 0.001), and negatively correlated with CD8+ T cell infiltration (r = -0.178, p < 0.001) (Figure 3B).