However, indicating a broader inflammatory response in the whole brain, transcripts encoding pro-inflammatory cytokines, such as interleukin-1α (IL-1α), interleukin-6 (IL-6), interleukin-8 (IL8/CXCL1), and especially MCP1/CCL2, exhibited significant upregulation at 2- or 4-days post-infection (Figure S7). This evidence concerns the gene CXCL1 and infection.