To substantiate the existence and outcomes of hyperglycemia and CH in experimental rats, the levels of blood HbA1c (Figure 6), serum NT-pro BNP (Figure 7), and LDH (Figure 8) were also monitored in the present study, all of which are associated with defective mitochondrial metabolism (Lichscheidt et al., 2022). The gene discussed is NPPB; the disease is cyclic hematopoiesis.