The mutated RDH12 mRNA, which is insensitive to NMD, produces a 40-amino-acid shorter protein, with a 17-amino-acid sequence shared with the two other variants previously reported in autosomal dominant RDH12-retinal diseases (Fingert et al., 2008; Muthiah et al., 2022). Here, RDH12 is linked to Abnormal retinal morphology.