Moreover, hCG’s pleiotropic effects (76), including its role in stimulating sex hormone production, reducing insulin resistance, improving hypothalamic function, increasing IGF-1 availability, and potentially alleviating mitochondrial dysfunction—as also evidenced by its ability to protect dopaminergic neurons from cell death in Parkinson’s disease models (127)—suggest a broad spectrum of therapeutic possibilities. The gene discussed is IGF1; the disease is Parkinson disease.