ECOG PS, Eastern Cooperative Oncology Group Performance Score; CCI, Charlson Comorbidity Index; FEV1, Forced Expiratory Volume in one second; eGFR, estimated glomerular filtration rate; CRP, C -reactive protein; GPS, Glasgow Prognostic Score; GNRI, Geriatric Nutritional Risk Index; F, female; M, Male; HT, hypertension; IHD, ischemic heart disease; MGUS, Monoclonal gammopathy of undetermined significance; IP, interstitial pneumonia; DM, diabetes mellitus. This evidence concerns the gene CRP and incontinentia pigmenti.