Takahashi et al. reported that platelet eluates from H. pylori-positive ITP patients recognized the cytotoxin-associated gene A (CagA), one of the H. pylori-derived proteins that determines virulence [15], but another group showed that platelet eluates from H. pylori-positive ITP patients that reacted with glycoprotein IIb/IIIa (GPIIb/IIIa) or GPIb were unable to recognize H. pylori antigens [16]. Here, S100A8 is linked to autoimmune thrombocytopenic purpura.