Currently, more than 30 genes associated with ALS have been identified, including the Cu/Zn superoxide dismutase 1 gene (SOD1), chromosome 9 open reading frame 72 gene (C9orf72), the gene coding TAR DNA binding protein 43 (TARDBP/TDP43), and fused in sarcoma (FUS) (Renton et al., 2014; Zufiría et al., 2016; Mejzini et al., 2019; Shatunov and Al-Chalabi, 2021; Chen et al., 2022). The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.