AIF1 and Alzheimer disease: Iba1 load was significantly disminished (52% ± 10.99% reduction) in the ipsilateral side of the 3xTg‐AD hippocampus injected with the old‐Tg mice brain homogenate in comparison with mice inoculated with the human brain extract (one‐way ANOVA, F(4, 20) = 3.673, p = 0.0212, Tukey's multiple comparisons tests, Figure 3A,B).