ALDH1A3 and cancer: Citral induces multiple anticancer molecular mechanisms that include the accumulation of ROS in cancer cells with subsequent DNA damages and the inhibition of tubulin polymerization and aldehyde dehydrogenase isoform ALDH1A3, which favors cancer proliferation and chemoresistance [10]; moreover, other minor components in lemongrass essential oil induce cytotoxic effects through various mechanisms.