Recognizing that systemic involvement in COVID-19 significantly increases morbidity and mortality, predictive scoring systems, such as COMPASS 19, are being developed to aid in the identification of patients at increased risk, utilizing platelet count, prothrombin time, antithrombin levels, CRP, D-dimer, total lymphocyte count, and hemoglobin [17]. The gene discussed is F2; the disease is COVID-19.