Notably, the negative correlation between prolactin and basal glucose levels, insulin resistance indices, and fasting leptin concentration, as well as the association of prolactin with a favorable lipid profile in the subgroup of women not developing T2D, suggested that prolactin levels might be closely linked to maternal glucose and lipid changes in the early postpartum period, likely influencing future T2D risk [70]. Here, PRL is linked to Insulin resistance.