A recent meta-analysis assessing the correlation between Lp(a) levels and the risk of stroke demonstrated that elevated Lp(a) levels were associated with an increased risk of ischemic stroke [standardized mean difference (SMD), 0.76; 95% CI, 0.53–0.99], particularly in the LAA subtype (SMD, 0.68; 95% CI, 0.01–1.34) [12]. The gene discussed is LPA; the disease is Stroke.