The laboratory findings revealed that both the ALT and AST levels were significantly higher only in the IBD-MASLD vs. IBD groups comparison (27 ± 26 vs. 19 ± 11 UI/L; p < 0.001 and 23 ± 12 vs. 20 ± 13 UI/L; p = 0.014, respectively), while TG levels were significantly higher in the IBD-MASLD group (118 ± 52 mg/dL) compared to the IBD-NAFLD (82 ± 15 mg/dL, p = 0.048) and IBD alone (95 ± 46 mg/dL, p < 0.001) groups. This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.