Results show that patients with depression had significantly higher increases at 2 years compared to baseline for all investigated parameters (CRP—p = 0.032/Fibrinogen—p = 0.030/Interleukin-6—p < 0.001/TNF-α -p = 0.007/Cortisol—p < 0.001). The gene discussed is CRP; the disease is depressive symptom measurement.