Dietary patterns rich in saturated fats, refined carbohydrates, and added sugars may contribute to the elevated non-HDL-C profiles observed in individuals with lower injuries by stimulating hepatic lipogenesis, increasing VLDL secretion, impairing lipoprotein clearance via reduced lipoprotein lipase activity, and diminishing reverse cholesterol transport, all of which exacerbate dyslipidemia [140]. This evidence concerns the gene LPL and metabolic syndrome.